⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568901 | 0.73 | — | — | |
| SCHEMBL8569381 | 0.67 | TP53 (0.31) | — | |
| SCHEMBL8565571 | 0.62 | KMT2A (0.34) | — | |
| SCHEMBL7830228 | 0.61 | ALDH1A1 (0.37) | — | |
| SCHEMBL8599821 | 0.59 | — | — | |
| SCHEMBL4723589 | 0.58 | GBA1 (0.39) | — | |
| SCHEMBL194886 | 0.58 | — | — | |
| SCHEMBL4722802 | 0.55 | CSNK1D (0.37) | — | |
| SCHEMBL144898 | 0.54 | — | — | |
| SCHEMBL11168114 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019369-B1 | ISOTHIOUREIDO ISOINDOLEDIONES, PROCESS FOR THEIR PREPARATION AND USE AS PLANT REGULATORS | Gulf Oil Corporation (US) | 1984-03-07 | — | — | EP | claimed |
| US-4292071-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1981-09-29 | — | — | US | claimed |
| EP-0019369-A1 | Isothioureido isoindolediones, process for their preparation and use as plant regulators | Gulf Oil Corporation (US) | 1980-11-26 | — | — | EP | claimed |
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |
| EP-0019369-B1 | ISOTHIOUREIDO ISOINDOLEDIONES, PROCESS FOR THEIR PREPARATION AND USE AS PLANT REGULATORS | Gulf Oil Corporation (US) | 1984-03-07 | — | — | EP | disclosed |
| US-4362879-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1982-12-07 | — | — | US | disclosed |
| US-4362879-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1982-12-07 | — | — | US | disclosed |
| US-4292071-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| US-4292071-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0019369-A1 | Isothioureido isoindolediones, process for their preparation and use as plant regulators | Gulf Oil Corporation (US) | 1980-11-26 | — | — | EP | disclosed |
| EP-0019369-A1 | Isothioureido isoindolediones, process for their preparation and use as plant regulators | Gulf Oil Corporation (US) | 1980-11-26 | — | — | EP | disclosed |