Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256760 | 0.89 | CYP2C9 (0.56) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL10899312 | 0.89 | CYP2C9 (0.56) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6696710 | 0.88 | CYP2C9 (0.54) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL27741569 | 0.86 | CYP2C9 (0.45) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL8053543 | 0.86 | CYP2C9 (0.53) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL11208867 | 0.86 | CYP2C9 (0.53) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL8600351 | 0.86 | CYP2C9 (0.53) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL11269373 | 0.85 | CYP2C9 (0.62) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL167038 | 0.85 | CYP2C9 (0.62) | CYP2C9ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7544282 | 0.84 | ALDH1A1 (0.45) | CYP2C9ALDH1A1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843951-A | Analgesic composition of pyrazolo(1,5-A) pyrimidines | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0795555-A1 | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-09-17 | — | — | EP | disclosed |