Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ERN1 | O75460 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499505 | 0.86 | ERN1 (0.54) | MAPTKMT2AMEN1ERN1LMNA | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.85 | MAPT (0.86) | MAPTKMT2AMEN1LMNAATM | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.85 | MAPT (0.86) | MAPTKMT2AMEN1LMNAATM | |
| SCHEMBL12560338 | 0.85 | ERN1 (0.63) | MAPTERN1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL25072701 | 0.85 | ALDH1A1 (0.65) | MAPTKMT2AMEN1ERN1LMNA | |
| SCHEMBL2040708 | 0.84 | CA12 (0.72) | ERN1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16991712 | 0.83 | ERN1 (0.55) | MAPTKMT2AMEN1ERN1ATM | |
| SCHEMBL7222505 | 0.83 | MAPT (0.64) | MAPTKMT2AMEN1LMNATSHR | |
| SCHEMBL8461881 | 0.83 | PDE4A (0.79) | — | |
| SCHEMBL19387238 | 0.82 | CA1 (0.70) | MAPTKMT2AMEN1ERN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846117-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040684-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |