Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.52 |
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268912 | 0.93 | MEN1 (0.49) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL8569827 | 0.93 | PDE4B (0.52) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL31432851 | 0.86 | CA12 (0.64) | KMT2AMEN1ALDH1A1CA12CA1 | |
| SCHEMBL903446 | 0.86 | CA12 (0.64) | KMT2AMEN1ALDH1A1CA12CA1 | |
| SCHEMBL8571660 | 0.85 | KMT2A (0.61) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL8570021 | 0.85 | MEN1 (0.61) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL7361467 | 0.83 | MEN1 (0.58) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL7396306 | 0.83 | MEN1 (0.58) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL8571467 | 0.83 | MEN1 (0.58) | KMT2AMEN1EPHX1PDE4BPDE4A | |
| SCHEMBL6816260 | 0.83 | KMT2A (0.58) | KMT2AMEN1EPHX1PDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710180-A | TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |