Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569255 | 1.00 | POLB (0.40) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8567079 | 0.80 | POLB (0.46) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8567076 | 0.80 | POLB (0.46) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8562157 | 0.78 | POLB (0.44) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8566398 | 0.78 | POLB (0.38) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8566394 | 0.78 | POLB (0.38) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8564990 | 0.76 | MGMT (0.39) | POLBSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8564994 | 0.76 | MGMT (0.39) | POLBSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8567732 | 0.75 | MAPT (0.45) | POLBRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL8567734 | 0.75 | MAPT (0.45) | POLBRAB9ASMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |