Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564990 | 1.00 | MGMT (0.39) | MGMTEGFRMAPTLMNAHPGD | |
| SCHEMBL8566394 | 0.85 | POLB (0.38) | EGFRMAPTLMNAHPGDPOLB | |
| SCHEMBL8566398 | 0.85 | POLB (0.38) | EGFRMAPTLMNAHPGDPOLB | |
| SCHEMBL8564063 | 0.83 | EGFR (0.39) | MGMTEGFRMAPTLMNAHPGD | |
| SCHEMBL8564067 | 0.83 | EGFR (0.39) | MGMTEGFRMAPTLMNAHPGD | |
| SCHEMBL8567128 | 0.80 | MAPT (0.39) | MGMTMAPTLMNAHPGDNPSR1 | |
| SCHEMBL8562134 | 0.80 | NFE2L2 (0.41) | MGMTMAPTLMNAPOLBALDH1A1 | |
| SCHEMBL8567126 | 0.80 | MAPT (0.39) | MGMTMAPTLMNAHPGDNPSR1 | |
| SCHEMBL8569251 | 0.76 | POLB (0.40) | MAPTLMNAPOLBALDH1A1HTT | |
| SCHEMBL8569255 | 0.76 | POLB (0.40) | MAPTLMNAPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |