SCHEMBL8569308

SCHEMBL8569308

CC[N+](CCOC)(CCOC)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 12/20 0.54
CHRNB4 P30926 8/20 0.54
CHRNA3 P32297 8/20 0.54
CHRNB2 P17787 6/20 0.50
CHRNA4 P43681 6/20 0.50
CYP1A2 P05177 2/20 0.44
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 2/20 0.41
MEN1 O00255 2/20 0.41
TP53 P04637 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
CYP2D6 P10635 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CHRM2 P08172 3/20 0.41
CHRNA10 Q9GZZ6 2/20 0.41
CHRNA9 Q9UGM1 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27343171 0.98 CHRNA7 (0.55) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL8054688 0.90 CHRNA7 (0.46) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL10452605 0.85 CHRNA7 (0.56) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL8569053 0.84 DNM1 (0.47) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
Bromide SCHEMBL30527250 0.81 CHRNA7 (0.57) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL30354177 0.81 CHRNA7 (0.54) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL8965697 0.80 CHRNA7 (0.41) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL8568870 0.80 CYP1A2 (0.49) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9183119 0.80 CHRNA7 (0.79) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
Bromide SCHEMBL2350742 0.80 CHRNA7 (0.54) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705674-A Process for preparing ortho-nitrobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-06 US disclosed