Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.74 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601861 | 0.86 | ACHE (0.78) | ACHECHRM4 | |
| SCHEMBL12043770 | 0.85 | ACHE (1.00) | ACHECHRM4 | |
| SCHEMBL429212 | 0.81 | ACHE (0.74) | ACHECHRM4BCHE | |
| SCHEMBL4636527 | 0.81 | ACHE (0.74) | ACHECHRM4BCHE | |
| SCHEMBL429213 | 0.81 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL4636524 | 0.81 | ACHE (0.74) | ACHECHRM4BCHE | |
| SCHEMBL31337447 | 0.81 | ACHE (0.63) | ACHECHRM4BCHE | |
| SCHEMBL29432097 | 0.81 | CHRM4 (1.00) | ACHECHRM4 | |
| SCHEMBL31337406 | 0.80 | ACHE (0.62) | ACHECHRM4BCHE | |
| SCHEMBL7808066 | 0.78 | ACHE (0.77) | ACHECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677516-B1 | Cyclic amide derivatives | EISAI CO LTD (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5654308-A | PREVENT OR TREAT DISEASE DUE TO INSUFFICIENT CHOLINE FUNCTION | EISAI CO., LTD. (JP) | 1997-08-05 | — | — | US | disclosed |
| US-5620976-A | PREVENTION AND TREATMENT OF DISEASES DUE TO INSUFFICIENCY OF THE CENTRAL CHOLINE FUNCTIONS | EISAI CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5521182-A | ACETYLCHOLINESTERASE INHIBITORS | EISAI CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0677516-A1 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5292735-A | Cyclic amide derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0468187-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1992-01-29 | — | — | EP | disclosed |