SCHEMBL8569441

Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)Nc4ccccc4)c3Cl)cccn2c1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	BDKRB2	P30411	18/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Hydrochloric Acid SCHEMBL8561903	0.99	BDKRB2 (1.00)	BDKRB2
SCHEMBL8566110	0.95	BDKRB2 (1.00)	BDKRB2
Hydrochloric Acid SCHEMBL8567462	0.94	BDKRB2 (1.00)	BDKRB2
SCHEMBL8567117	0.94	BDKRB2 (0.89)	BDKRB2
SCHEMBL8561576	0.94	BDKRB2 (0.90)	BDKRB2
Hydrochloric Acid SCHEMBL8567951	0.94	BDKRB2 (0.89)	BDKRB2
Hydrochloric Acid SCHEMBL8566043	0.94	BDKRB2 (0.90)	BDKRB2
SCHEMBL8562621	0.93	BDKRB2 (0.88)	BDKRB2
SCHEMBL8559745	0.93	BDKRB2 (1.00)	BDKRB2
SCHEMBL8566132	0.93	BDKRB2 (1.00)	BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0596406-B1	Imidazo (1,2-a) Pyridines as bradykinin antagonists	FUJISAWA PHARMACEUTICAL CO (JP)	1998-12-16	—	—	EP	disclosed
US-5574042-A	ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN	FUJISAWA PHARMACEUTICAL CO., LTD (JP)	1996-11-12	—	—	US	disclosed
EP-0596406-A1	Imidazo (1,2-a) Pyridines as bradykinin antagonists	FUJISAWA PHARMACEUTICAL CO., LTD. (JP)	1994-05-11	—	—	EP	disclosed