Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572968 | 0.83 | GRIN2D (0.46) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3682386 | 0.81 | GRIN2D (0.56) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3714145 | 0.79 | CETP (0.57) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6966650 | 0.77 | CHRM3 (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3676553 | 0.76 | PTPN11 (0.47) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL6969378 | 0.76 | GBA1 (0.49) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL8573962 | 0.76 | GRIN2D (0.42) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8573444 | 0.75 | GRIN2D (0.53) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL8573957 | 0.75 | SMN1; SMN2 (0.44) | CETPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8572810 | 0.74 | DRD1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1102144-C | Noval pyrimidine derivatives and prepn. processes thereof | YUHAN CORP (KR) | 2003-02-26 | — | — | CN | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| CN-1155281-A | Noval pyrimidine derivatives and prepn. processes thereof | YUHAN CORP (KR) | 1997-07-23 | — | — | CN | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |