Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997338 | 0.84 | PDE4A (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7960352 | 0.82 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6966656 | 0.81 | CHRM3 (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL6969378 | 0.79 | GBA1 (0.49) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8117433 | 0.78 | FAAH (0.35) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8109958 | 0.78 | CHRM3 (0.35) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8569458 | 0.77 | CETP (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3641040 | 0.77 | GBA1 (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6991703 | 0.77 | CHRM3 (0.44) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL6961503 | 0.76 | CHRM3 (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118464-C | Noval pyrimidine derivatives and process and preparing thereof | YUHAN CORP (KR) | 2003-08-20 | — | — | CN | disclosed |
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| CN-1251586-A | Noval pyrimidine derivatives and process and preparing thereof | YUHAN CORP (KR) | 2000-04-26 | — | — | CN | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |