Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855580 | 0.82 | FOLH1 (0.49) | EGLN3 | |
| SCHEMBL19742218 | 0.82 | FOLH1 (0.49) | EGLN3 | |
| SCHEMBL19742219 | 0.82 | FOLH1 (0.49) | EGLN3 | |
| SCHEMBL14796565 | 0.78 | CYP26A1 (0.37) | TBXAS1AGTR2ALDH1A1CYP26A1EGLN3 | |
| SCHEMBL10402927 | 0.77 | CYP26A1 (0.40) | ALDH1A1CYP26A1 | |
| SCHEMBL23067830 | 0.76 | P2RY12 (0.38) | — | |
| SCHEMBL17512450 | 0.76 | CYP3A4 (0.40) | TBXAS1 | |
| SCHEMBL6808774 | 0.76 | KMT2A (0.41) | ALDH1A1CYP26A1EGLN3 | |
| SCHEMBL22649178 | 0.75 | AHR (0.33) | TBXAS1POLBALDH1A1 | |
| SCHEMBL9913350 | 0.74 | TBXAS1 (0.34) | TBXAS1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358901-B | Deuterated pent-4-enyl-N-furfuryl-NPreparation of (E) -imidazole-1-carbonyl-DL-homoalanine ester and bactericidal activity | 中国农业大学 | 2021-09-14 | — | — | CN | disclosed |
| EP-0586393-B1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |
| US-5739133-A | N-ACYLATED AND ALKYLATED DERIVATIVES OF PYRIDAZINO(4,5-B)-QUINOLINES; EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS; STROKES; ANTIISCHEMIC AND HYPOGLYCEMIC AGENTS; PSYCHOSIS; NEUROGODEGENERATIVE DISORDERS | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| US-5733910-A | Pyridazinedione compounds useful in the treating neurological disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-03-31 | — | — | US | disclosed |
| US-5604227-A | EXCITATORY AMINO ACID ANTAGONIST; MONO, DI OR TRI-ACETYLATION OR ALKYLATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-02-18 | — | — | US | disclosed |
| US-5599814-A | SUBSTITUTED PYRIDAZINO(4,5-B)QUINOLINES AS ANTAGONISTS OF EXCITATORY AMINO ACIDS | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1997-02-04 | — | — | US | disclosed |
| EP-0516297-B1 | Pyridazinediones and their use in the treatment of neurological disorders | ZENECA LTD (GB) | 1996-10-30 | — | — | EP | disclosed |
| EP-0341845-B1 | Fungicides | ZENECA LTD (GB) | 1995-06-21 | — | — | EP | disclosed |
| EP-0516297-A1 | Pyridazinediones and their use in the treatment of neurological disorders | ZENECA LIMITED (GB) | 1992-12-02 | — | — | EP | disclosed |
| EP-0341845-A2 | Fungicides | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |