Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.44 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.44 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.44 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.44 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449011 | 0.89 | CCNT1 (0.53) | PDE10APIK3CGCCNT1CDK9ALDH1A3 | |
| SCHEMBL8574299 | 0.83 | PIK3CG (0.51) | PDE10APIK3CGCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7843308 | 0.83 | CCNT1 (0.45) | CYP1B1CYP1A1PIK3CGCYP1A2CYP2E1 | |
| SCHEMBL8570252 | 0.81 | PDE10A (0.56) | PDE10APIK3CGCYP2C19CCNT1CDK9 | |
| SCHEMBL12953045 | 0.81 | PIK3CG (0.67) | PDE10APIK3CGALDH1A3NPC1RAB9A | |
| SCHEMBL14545875 | 0.79 | PIK3CG (0.55) | PDE10APIK3CGNPC1RAB9AKCNN3 | |
| SCHEMBL14395147 | 0.78 | PIK3CG (0.54) | PDE10APIK3CGCCNT1CDK9NPC1 | |
| SCHEMBL312516 | 0.77 | PDE10A (0.64) | PDE10APIK3CGALDH1A3NPC1RAB9A | |
| SCHEMBL5460421 | 0.77 | PDE10A (0.59) | PDE10APIK3CGNPC1RAB9AKCNN3 | |
| SCHEMBL12953057 | 0.76 | PDE10A (0.50) | PDE10APIK3CGCCNT1CDK9KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843951-A | Analgesic composition of pyrazolo(1,5-A) pyrimidines | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0795555-A1 | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-09-17 | — | — | EP | disclosed |