Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 3/20 | 0.45 |
| ▸ | HTR1B | P28222 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598857 | 0.86 | HTR1F (0.81) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| Bromide SCHEMBL7138690 | 0.85 | HTR1F (0.80) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| SCHEMBL7144771 | 0.85 | HTR1F (0.83) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| SCHEMBL7143303 | 0.84 | HTR1F (1.00) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| SCHEMBL8196218 | 0.83 | HTR1F (0.75) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| SCHEMBL7140234 | 0.83 | HTR1F (0.77) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7138726 | 0.83 | HTR1F (0.98) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7140335 | 0.82 | HTR1F (0.76) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| SCHEMBL7141203 | 0.81 | HTR1F (0.73) | HTR1FMAPTHTR1AHTR1DHTR1B | |
| Malonic Acid SCHEMBL8215354 | 0.81 | HTR1F (0.70) | HTR1FMAPTHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006402-A1 | TREATMENT OF THE COMMON COLD OR ALLERGIC RHINITIS | ELI LILLY AND COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |