Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016729 | 0.86 | POLB (0.55) | KEAP1KMT2AGAAL3MBTL1EGLN1 | |
| SCHEMBL8569753 | 0.83 | KEAP1 (0.50) | KEAP1KMT2AGAAL3MBTL1EGLN1 | |
| SCHEMBL31448014 | 0.82 | KEAP1 (0.62) | KEAP1KMT2AGAAEGLN1FTO | |
| SCHEMBL13196121 | 0.79 | GAA (0.62) | KMT2AGAAL3MBTL1HPGDHSD17B10 | |
| SCHEMBL27450922 | 0.77 | KEAP1 (0.66) | KEAP1KMT2AGAAEGLN1LMNA | |
| SCHEMBL30289977 | 0.77 | KMT2A (0.65) | KEAP1KMT2AEGLN1HPGDHSD17B10 | |
| Salicyluric Acid SCHEMBL29935452 | 0.75 | HPGD (0.58) | KEAP1KMT2AGAAEGLN1HPGD | |
| Salicyluric Acid SCHEMBL570541 | 0.75 | HPGD (0.58) | KEAP1KMT2AGAAEGLN1HPGD | |
| SCHEMBL7016717 | 0.74 | KMT2A (0.44) | KEAP1KMT2AGAAL3MBTL1EGLN1 | |
| SCHEMBL8761962 | 0.74 | POLB (0.68) | GAAL3MBTL1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828488-A1 | ISOTHIAZOLONES | WARNER-LAMBERT COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038144-A1 | ISOTHIAZOLONES | WARNER-LAMBERT COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |