Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569790 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL8568454 | 0.91 | MTNR1A (0.50) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL8561678 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL7418106 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL7418105 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL8568800 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL13313179 | 0.79 | IDO1 (0.63) | IDO1AKR1C3CYP19A1GAA | |
| SCHEMBL8562997 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL8562991 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BIDO1EPHX2MEN1 | |
| SCHEMBL13305786 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BIDO1EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |