Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572374 | 0.95 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1554160 | 0.82 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| Hydrochloric Acid SCHEMBL8576071 | 0.81 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1553435 | 0.80 | PDE4D (0.45) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL8575380 | 0.79 | HSD17B10 (0.46) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8572881 | 0.79 | HSD17B10 (0.46) | HSD17B10STING1AMY1AADORA2AKDM4E | |
| SCHEMBL8576057 | 0.79 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1554161 | 0.79 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL2458459 | 0.77 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1552957 | 0.77 | PDE4D (0.54) | PDE4APDE4BPDE4CPDE4DPBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |