Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570207 | 1.00 | KCNH2 (0.36) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL10580188 | 0.88 | KCNH2 (0.30) | KCNH2 | |
| SCHEMBL10580193 | 0.88 | KCNH2 (0.30) | KCNH2 | |
| SCHEMBL8569840 | 0.88 | — | — | |
| SCHEMBL8569842 | 0.88 | — | — | |
| SCHEMBL10332929 | 0.87 | KCNH2 (0.36) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL10773963 | 0.87 | KCNH2 (0.36) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL2456038 | 0.86 | KCNH2 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL3833502 | 0.86 | KCNH2 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL3833505 | 0.86 | KCNH2 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773624-A | Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0795551-A1 | Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1997-09-17 | — | — | EP | disclosed |
| EP-0099553-B1 | CEPHEM COMPOUNDS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-27 | — | — | EP | disclosed |
| US-4772682-A | THIOCYANATE AND SULFONIUM SUBSTITUTED | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-20 | — | — | US | disclosed |
| US-4654422-A | Cephem intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-31 | — | — | US | disclosed |
| US-4563449-A | BACTERICIDAL ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0099553-A2 | Cephem compounds, process and intermediates for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |