Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833505 | 1.00 | KCNH2 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL3833502 | 1.00 | KCNH2 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL10773963 | 0.90 | KCNH2 (0.36) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL10332929 | 0.90 | KCNH2 (0.36) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL10837303 | 0.89 | ALDH1A1 (0.33) | KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL9779227 | 0.89 | ALDH1A1 (0.33) | KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL9779233 | 0.89 | ALDH1A1 (0.33) | KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL10782782 | 0.88 | ALDH1A1 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| SCHEMBL10782787 | 0.88 | ALDH1A1 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT | |
| Hydrochloric Acid SCHEMBL8763432 | 0.87 | KCNH2 (0.35) | KCNH2ALDH1A1MEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585872-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | claimed |
| EP-0036673-B1 | NEW THIADIAZOL COMPOUNDS AND PROCESSES FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-11 | — | — | EP | claimed |
| JP-2076865-A | — | — | None | — | — | JP | disclosed |
| CN-121181573-B | Cephalosporium containing C-3 tetrahydrofuran derivative and application thereof | 重庆汉佩生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-20140350240-A1 | PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2014-11-27 | — | — | US | disclosed |
| EP-2788361-A1 | PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF | Ranbaxy Laboratories Limited (IN) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013084171-A1 | PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2013-06-13 | — | — | WO | disclosed |
| US-8445476-B2 | Carbacephem β-lactam antibiotics | ACHAOGEN, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010123997-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-21 | — | — | US | disclosed |
| EP-0062321-A2 | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4338313-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| US-4332800-A | BACTERICIDES CONTAINING 7-AMINOTHIADIAZOLE GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0042154-A1 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-23 | — | — | EP | disclosed |
| EP-0036673-A1 | New thiadiazol compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-30 | — | — | EP | disclosed |
| US-4268509-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-19 | — | — | US | disclosed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | disclosed |
| EP-0013762-A2 | Cephem and cepham compounds, processes for their preparation, pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-06 | — | — | EP | disclosed |
| EP-0007470-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | KCNH2 3039/4885ALDH1A1 2455/4885MEN1 2327/4885 |
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | KCNH2 3205/4885ALDH1A1 2468/4885MEN1 2194/4885 |
| US-20140350240-A1 | PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF | CYP3A7, SEPTIN7, UGT1A7 | KCNH2 969/4885ALDH1A1 2155/4885MEN1 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.