Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982459 | 0.95 | HPGD (0.45) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL21199747 | 0.87 | POLB (0.46) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL8564545 | 0.87 | HPGD (0.45) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL5050275 | 0.87 | HPGD (0.42) | HPGDALDH1A1LMNAPRNPRECQL | |
| Hydrochloric Acid SCHEMBL5724631 | 0.85 | HPGD (0.41) | HPGDALDH1A1LMNAPRNPRECQL | |
| Hydrochloric Acid SCHEMBL2413233 | 0.85 | HPGD (0.40) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL8982537 | 0.84 | HPGD (0.40) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL2179325 | 0.83 | RXFP1 (0.66) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL2162296 | 0.83 | HPGD (0.52) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL4179468 | 0.83 | HPGD (0.40) | HPGDALDH1A1LMNAPRNPRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530579-B1 | Condensed pyrimidine derivatives antitumor agents | EISAI CO LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5688800-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5554615-A | ANTITUMOR | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0530579-A1 | Condensed pyrimidine derivatives antitumor agents | Eisai Co., Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |