Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277926 | 0.92 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8573971 | 0.90 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL9276133 | 0.90 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7353707 | 0.87 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7361167 | 0.86 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30530004 | 0.85 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7363289 | 0.85 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7352136 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8574005 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7356142 | 0.83 | PDE4B (0.42) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710180-A | TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |