Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570246 | 0.80 | LTB4R (0.69) | LTB4RLTB4R2 | |
| SCHEMBL8599326 | 0.80 | LTB4R (0.69) | LTB4RLTB4R2 | |
| SCHEMBL8420032 | 0.79 | LTB4R (0.66) | LTB4RLTB4R2 | |
| SCHEMBL7986719 | 0.79 | LTB4R (0.66) | LTB4RLTB4R2 | |
| SCHEMBL7976153 | 0.79 | LTB4R (0.66) | LTB4RLTB4R2 | |
| SCHEMBL8422443 | 0.76 | LTB4R (0.60) | LTB4RLTB4R2 | |
| SCHEMBL7987593 | 0.74 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL7987594 | 0.74 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL7987586 | 0.74 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8418446 | 0.72 | LTB4R (0.65) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942903-A1 | ARYL-SUBSTITUTED ACRYLAMIDES WITH LEUKOTRIENE B4 (LTB-4) RECEPTOR ANTAGONIST ACTIVITY | Novartis AG (CH) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998013347-A1 | ARYL-SUBSTITUTED ACRYLAMIDES WITH LEUKOTRIENE B4 (LTB-4) RECEPTOR ANTAGONIST ACTIVITY | NOVARTIS AG (CH) | 1998-04-02 | — | — | WO | disclosed |