SCHEMBL8570487

SCHEMBL8570487

CCCC[C@]1(CC)CS(=O)(=O)c2ccc(OC)cc2[C@H](c2ccc(F)cc2)[C@@H]1O

nearest known ligand 0.93

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6827670 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL6222167 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL6224133 0.91 SLC10A2 (0.84) SLC10A2
SCHEMBL6314538 0.91 SLC10A2 (0.84) SLC10A2
SCHEMBL6827034 0.90 SLC10A2 (1.00) SLC10A2
SCHEMBL6219399 0.90 SLC10A2 (1.00) SLC10A2
SCHEMBL6823727 0.90 SLC10A2 (1.00) SLC10A2
SCHEMBL6221311 0.90 SLC10A2 (0.86) SLC10A2
SCHEMBL6259037 0.90 SLC10A2 (0.81) SLC10A2
SCHEMBL6222638 0.90 SLC10A2 (0.81) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033882-A9 NOVEL BENZOTHIEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT AND TAUROCHOLATE UPTAKE 1998-02-26 WO disclosed