Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | PGC | P20142 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227028 | 1.00 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5401511 | 0.91 | CYP3A4 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8562897 | 0.90 | MMP2 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL12510780 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL668266 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL668267 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL14613663 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL14044444 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL8170296 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Droxinavir SCHEMBL29636917 | 0.89 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558630-B1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO CO (US) | 1998-04-08 | — | — | EP | claimed |
| EP-0711224-A1 | METHOD OF PRODUCING RECORDED IMAGES | EASTMAN KODAK COMPANY (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995032871-A1 | METHOD OF PRODUCING RECORDED IMAGES | EASTMAN KODAK COMPANY (US) | 1995-12-07 | — | — | WO | disclosed |
| WO-1995030547-A1 | RECORDING PROCESS | EASTMAN KODAK COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |