Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570557 | 1.00 | SCN5A (0.38) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| SCHEMBL8570562 | 1.00 | SCN5A (0.38) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL7501189 | 0.99 | SCN5A (0.38) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL7501184 | 0.99 | SCN5A (0.38) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL7502749 | 0.99 | SCN5A (0.38) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| SCHEMBL8570480 | 0.89 | SCN5A (0.39) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| SCHEMBL8577579 | 0.89 | SCN5A (0.39) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| SCHEMBL8572099 | 0.89 | SCN5A (0.39) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| SCHEMBL8572102 | 0.89 | SCN5A (0.39) | SCN5AKCNH2POLBALDH1A1CHRM2 | |
| SCHEMBL8575693 | 0.89 | SCN5A (0.39) | SCN5AKCNH2POLBALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |