Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7502911 | 0.99 | KCNH2 (0.37) | KCNH2SCN5ALMNAFFAR4KDM4E | |
| SCHEMBL8577656 | 0.95 | KCNH2 (0.40) | KCNH2SCN5AFFAR4KDM4E | |
| SCHEMBL8574325 | 0.95 | KCNH2 (0.40) | KCNH2SCN5AFFAR4KDM4E | |
| Hydrochloric Acid SCHEMBL7495496 | 0.94 | KCNH2 (0.40) | KCNH2SCN5AFFAR4KDM4E | |
| Hydrochloric Acid SCHEMBL7503660 | 0.94 | KCNH2 (0.40) | KCNH2SCN5AFFAR4KDM4E | |
| Hydrochloric Acid SCHEMBL9076010 | 0.91 | SCN5A (0.38) | KCNH2SCN5ALMNAKDM4ESCN7A | |
| SCHEMBL8600110 | 0.88 | KCNH2 (0.42) | KCNH2SCN5ALMNAKDM4E | |
| SCHEMBL7503117 | 0.87 | SCN5A (0.39) | KCNH2SCN5ALMNAFFAR4KDM4E | |
| Hydrochloric Acid SCHEMBL7545787 | 0.87 | KCNH2 (0.41) | KCNH2SCN5ALMNAKDM4E | |
| SCHEMBL7507996 | 0.87 | FFAR4 (0.34) | KCNH2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | claimed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |