Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574325 | 1.00 | KCNH2 (0.40) | KCNH2SCN5ATOP1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7503660 | 0.99 | KCNH2 (0.40) | KCNH2SCN5ATOP1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7495496 | 0.99 | KCNH2 (0.40) | KCNH2SCN5ATOP1KDM4EALDH1A1 | |
| SCHEMBL8570709 | 0.95 | KCNH2 (0.38) | KCNH2SCN5AKDM4EFFAR4 | |
| Hydrochloric Acid SCHEMBL7502911 | 0.94 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL8574368 | 0.92 | SCN5A (0.40) | KCNH2SCN5ATOP1FFAR4 | |
| SCHEMBL8574291 | 0.92 | SCN5A (0.41) | KCNH2SCN5ATOP1 | |
| SCHEMBL8574285 | 0.92 | SCN5A (0.41) | KCNH2SCN5ATOP1 | |
| Hydrochloric Acid SCHEMBL8572865 | 0.91 | SCN5A (0.39) | KCNH2SCN5ATOP1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7497986 | 0.91 | SCN5A (0.40) | KCNH2SCN5ATOP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |