Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021564 | 0.92 | KMT2A (0.58) | MITFKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8803877 | 0.84 | KMT2A (0.61) | KMT2AALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL7017263 | 0.84 | MAPT (0.47) | KMT2AALDH1A1CYP3A4POLBMEN1 | |
| SCHEMBL4639794 | 0.78 | ALDH1A1 (0.57) | KMT2AALDH1A1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL346217 | 0.77 | KMT2A (0.64) | MITFKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22890327 | 0.77 | KMT2A (0.64) | MITFKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14067634 | 0.76 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL6398309 | 0.76 | KMT2A (0.71) | MITFKMT2AALDH1A1LMNASMN1; SMN2 | |
| Methane SCHEMBL28308571 | 0.74 | KMT2A (0.69) | MITFKMT2AALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29079546 | 0.74 | KMT2A (0.69) | MITFKMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828488-A1 | ISOTHIAZOLONES | WARNER-LAMBERT COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038144-A1 | ISOTHIAZOLONES | WARNER-LAMBERT COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |