Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607973 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL13516887 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL23750675 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL3736036 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL2001275 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL4456075 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL3734720 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL3734717 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL697621 | 0.83 | ALDH1A1 (0.61) | ALDH1A1HTTLDHANPC1POLB | |
| SCHEMBL292834 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HTTLDHANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719139-A | BACTERICIDES | ZENECA LIMITED (GB) | 1998-02-17 | — | — | US | disclosed |
| EP-0722945-A1 | 9-oxo-1-azabicyclo(5.2.0)non-2,3-diene-2-carboxylic acid derivatives as antibiotics | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |