Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071233 | 0.84 | TDP1 (0.61) | TDP1SMN1; SMN2GPR35TSHRALDH1A1 | |
| SCHEMBL1970696 | 0.78 | TDP1 (0.54) | TDP1SMN1; SMN2GPR35TSHRALDH1A1 | |
| SCHEMBL29448254 | 0.78 | TDP1 (0.60) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| SCHEMBL24548 | 0.78 | TDP1 (0.60) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| 2-Nitroaniline SCHEMBL6000 | 0.78 | PDE7A (0.62) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| 2-Nitroaniline SCHEMBL29396517 | 0.78 | PDE7A (0.62) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| SCHEMBL10381945 | 0.78 | PDE7A (0.62) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| SCHEMBL17934 | 0.77 | TSHR (0.59) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| 2-Nitroaniline SCHEMBL859788 | 0.76 | PDE7A (0.60) | TDP1SMN1; SMN2PDE7AGPR35TSHR | |
| 2-Nitroaniline SCHEMBL5331149 | 0.76 | PDE7A (0.60) | TDP1SMN1; SMN2PDE7AGPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998024776-A1 | PREPARATION OF AN AMINOARYLAMINOARAZOLE | THE DOW CHEMICAL COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5739344-A | Preparation of an aminoarylaminoarazole | THE DOW CHEMICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |