Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.64 |
| ▸ | NQO2 | P16083 | 12/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435532 | 1.00 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8431981 | 0.93 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8606216 | 0.93 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8990668 | 0.89 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8572818 | 0.89 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8573856 | 0.85 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8990805 | 0.85 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8574906 | 0.85 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8432485 | 0.85 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8570206 | 0.83 | MTNR1A (0.47) | MTNR1AMTNR1BNQO2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5780512-A | MELATONINERGIC | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |
| US-5693665-A | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |