Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.32 |
| ▸ | ADH1C | P00326 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885312 | 0.70 | CYP1A2 (0.38) | CYP1A2 | |
| SCHEMBL14499455 | 0.69 | CYP1A2 (0.43) | CYP1A2 | |
| SCHEMBL14499454 | 0.69 | CYP1A2 (0.43) | CYP1A2 | |
| SCHEMBL14499453 | 0.69 | CYP1A2 (0.43) | CYP1A2 | |
| SCHEMBL27723452 | 0.69 | HSD17B10 (0.40) | — | |
| SCHEMBL21884120 | 0.68 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL21884133 | 0.67 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL6823815 | 0.67 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL21884149 | 0.66 | — | — | |
| Formamide SCHEMBL4415470 | 0.65 | HPGD (0.35) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931078-A1 | NOVEL TRICYCLIC PIPERIDINYL COMPOUNDS USEFUL AS INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998011098-A1 | NOVEL TRICYCLIC PIPERIDINYL COMPOUNDS USEFUL AS INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1998-03-19 | — | — | WO | disclosed |