Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13177605 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL17716550 | 0.76 | ERAP1 (0.41) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL17716531 | 0.76 | ERAP1 (0.38) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL17716549 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL17716534 | 0.75 | ERAP1 (0.37) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL10026038 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL22702331 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL17716514 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL16645386 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL8568000 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830912-A | Derivatives of 6,8-difluoro-7-hydroxycoumarin | MOLECULAR PROBES, INC. (US) | 1998-11-03 | — | — | US | disclosed |