Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716552 | 0.81 | MAOB (0.38) | ERAP1KCNA3CNR2PGRFNTA | |
| SCHEMBL17716531 | 0.79 | ERAP1 (0.38) | ERAP1KCNA3CNR2KDM4EALDH1A1 | |
| SCHEMBL17716534 | 0.78 | ERAP1 (0.37) | ERAP1KCNA3CNR2KDM4EALDH1A1 | |
| SCHEMBL8571644 | 0.76 | KDM4E (0.51) | ERAP1CNR2KDM4EALDH1A1NPC1 | |
| SCHEMBL13177605 | 0.75 | KDM4E (0.48) | ERAP1CNR2KDM4EALDH1A1KMT2A | |
| SCHEMBL17716548 | 0.72 | ERAP1 (0.50) | ERAP1KCNA3PGRKDM4EALDH1A1 | |
| SCHEMBL19085443 | 0.71 | KDM4E (0.41) | ERAP1CNR2KDM4EALDH1A1KMT2A | |
| SCHEMBL17716549 | 0.70 | KDM4E (0.66) | ERAP1CNR2KDM4EALDH1A1KMT2A | |
| SCHEMBL17716545 | 0.68 | USP2 (0.46) | KCNA3KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL16645386 | 0.68 | KDM4E (0.56) | ERAP1CNR2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION | 2020-06-18 | — | — | US | disclosed |
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | MPI, TIPRL, BAZ1A | ERAP1 3627/4885KCNA3 4446/4885CNR2 4048/4885 |
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | ZYX, MPI, BAZ1A | ERAP1 3604/4885KCNA3 4294/4885CNR2 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.