Aniline

Aniline

SCHEMBL8571982

Nc1ccccc1.O=[PH](O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
CYP3A4 P08684 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
HSD17B10 Q99714 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
PBRM1 Q86U86 1/20 0.43
MAPT P10636 7/20 0.40
MAOA P21397 5/20 0.40
MAOB P27338 3/20 0.40
CYP2C19 P33261 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
HTT P42858 2/20 0.40
RAB9A P51151 2/20 0.40
PKM P14618 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL27762408 0.86 MAPT (0.64) TSHRCYP3A4TDP1HSD17B10MAPT
Phosphonic Acid SCHEMBL28877657 0.84 MAPT (0.57) TSHRCYP3A4TDP1HSD17B10MAPT
Aniline SCHEMBL22528486 0.84 TSHR (0.92) TSHRCYP3A4TDP1HSD17B10TAAR1
Aniline SCHEMBL28119661 0.83 TSHR (0.50) TSHRCYP3A4TDP1HSD17B10TAAR1
Aniline SCHEMBL6049858 0.81 TSHR (0.73) TSHRCYP3A4TDP1HSD17B10TAAR1
Aniline SCHEMBL8413315 0.81 TSHR (0.73) TSHRCYP3A4TDP1HSD17B10TAAR1
Aniline SCHEMBL27831713 0.81
Aniline SCHEMBL9135530 0.81
SCHEMBL18517570 0.80 TSHR (1.00) TSHRCYP3A4TDP1HSD17B10TAAR1
Aniline SCHEMBL16922171 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110064438-A A kind of NiO composite photo-catalyst and its preparation method and application of organic phospho acid modification 山东大学 2019-07-30 CN claimed
EP-0429614-B1 AZOPHENYL COMPOUNDS JAMES ROBINSON LTD (GB) 1995-10-11 EP claimed
EP-0429614-A1 AZOPHENYL COMPOUNDS. JAMES ROBINSON LTD (GB) 1991-06-05 EP claimed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO claimed
CN-101962496-B Preparation method of modified azo yellow pigment derivative dispersant, prepared derivative dispersant and application thereof WINBOS NEW MATERIALS CO LTD 2012-05-23 CN disclosed
CN-101962496-A Preparation method of modified azo yellow pigment derivative dispersant as well as prepared derivative dispersant and application thereof WINBOS NEW MATERIALS CO LTD 2011-02-02 CN disclosed
US-5719270-A DYES, INTERMEDIATES PARTINGTON STEVEN MICHAEL (GB) 1998-02-17 US disclosed
EP-0429614-B1 AZOPHENYL COMPOUNDS JAMES ROBINSON LTD (GB) 1995-10-11 EP disclosed
EP-0429614-A1 AZOPHENYL COMPOUNDS. JAMES ROBINSON LTD (GB) 1991-06-05 EP disclosed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO disclosed
US-4472308-A Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group ICI UNITED STATES, INC. (US) 1984-09-18 US disclosed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed
US-4134722-A Reactive dyeing system using phosphorus acid dyes with a cyanamide compound BURLINGTON INDUSTRIES, INC. (US) 1979-01-16 US disclosed