Phosphonic Acid

Phosphonic Acid

SCHEMBL28877657

Nc1ccc(N)cc1.O=[PH](O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 6/20 0.50
ALOX15 P16050 2/20 0.50
CA6 P23280 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA3 P07451 1/20 0.50
THRB P10828 1/20 0.50
CASP1 P29466 1/20 0.50
HIF1A Q16665 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MASP2 O00187 1/20 0.48
PLAU P00749 1/20 0.48
THPO P40225 1/20 0.48
TDP1 Q9NUW8 4/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 7/20 0.46
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Aminophenol SCHEMBL11869482 0.88 ALDH1A1 (0.72) MAPTMEN1KMT2AALDH1A1CYP3A4
4-Bromoaniline SCHEMBL27329072 0.86 ALDH1A1 (0.68) MAPTMEN1KMT2AALDH1A1CYP3A4
Phosphonic Acid SCHEMBL28977568 0.86 MAPT (0.42) MAPTMEN1KMT2AALDH1A1CYP3A4
Aniline SCHEMBL8571982 0.84 TSHR (0.65) MAPTMEN1KMT2AALDH1A1CYP3A4
Phosphonic Acid SCHEMBL8373199 0.84 APP (0.62) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL7205093 0.82 MAPT (0.44) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL8651169 0.76 ALDH1A1 (0.46) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL27981 0.76
SCHEMBL320609 0.76 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1CYP3A4
Bicarbonate SCHEMBL10433540 0.74 MAPT (0.61) MAPTMEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343256-B Functionalized covalent organic framework material and preparation method and application thereof 四川大学 2024-02-13 CN claimed
CN-117343256-A Functionalized covalent organic framework material and preparation method and application thereof 四川大学 2024-01-05 CN claimed
CN-117343256-B Functionalized covalent organic framework material and preparation method and application thereof 四川大学 2024-02-13 CN disclosed
CN-117343256-A Functionalized covalent organic framework material and preparation method and application thereof 四川大学 2024-01-05 CN disclosed
CN-115138220-A Anionic covalent organic framework membrane and preparation and application thereof 天津大学 2022-10-04 CN disclosed