Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572008 | 1.00 | NPSR1 (0.33) | NPSR1ALDH1A1KDM4E | |
| SCHEMBL8573875 | 0.76 | ALOX5 (0.36) | NPSR1ALDH1A1KDM4E | |
| SCHEMBL8573869 | 0.76 | ALOX5 (0.36) | NPSR1ALDH1A1KDM4E | |
| SCHEMBL21366056 | 0.73 | NPSR1 (0.40) | NPSR1ALDH1A1KDM4E | |
| SCHEMBL9016599 | 0.71 | GAA (0.32) | — | |
| SCHEMBL9876380 | 0.71 | GAA (0.32) | — | |
| SCHEMBL8761670 | 0.69 | CA1 (0.41) | ALDH1A1 | |
| SCHEMBL8761680 | 0.69 | CA1 (0.41) | ALDH1A1 | |
| SCHEMBL10851479 | 0.69 | — | — | |
| SCHEMBL11116629 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |