⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873801 | 0.95 | — | — | |
| SCHEMBL28291388 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL8686366 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL18189712 | 0.91 | ALDH1A1 (0.31) | — | |
| SCHEMBL28492986 | 0.87 | — | — | |
| SCHEMBL3731421 | 0.78 | — | — | |
| SCHEMBL2307969 | 0.78 | — | — | |
| SCHEMBL11106192 | 0.78 | FFAR3 (0.32) | — | |
| Ethane SCHEMBL11430474 | 0.75 | — | — | |
| Ethane SCHEMBL10960831 | 0.75 | FFAR3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308145-A2 | Mylbemycin derivatives with antiparasitic activity | Pfizer Limited (GB) | 1989-03-22 | — | — | EP | claimed |
| US-5840704-A | INSECTICIDES, MITICIDES, ANTHELMINTICS | PFIZER INC. (US) | 1998-11-24 | — | — | US | disclosed |
| US-5451511-A | Biosynthesis, avermectins | PFIZER INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5089480-A | ANTIPARASITIC AGENTS | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-5026643-A | On carboxylic acid substrate | PFIZER INC. (US) | 1991-06-25 | — | — | US | disclosed |
| US-4929638-A | INSECTICIDES, ANTHELMINTICS | PFIZER INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4927847-A | PARASITICIDES | PFIZER INC. (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0308145-A2 | Mylbemycin derivatives with antiparasitic activity | Pfizer Limited (GB) | 1989-03-22 | — | — | EP | disclosed |
| EP-0214731-A2 | Antiparasitic avermectin and milbemycin derivatives and process for their preparation | Pfizer Limited (GB) | 1987-03-18 | — | — | EP | disclosed |