Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467896 | 0.90 | ESR1 (0.34) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL16603060 | 0.84 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL17069893 | 0.83 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL121414 | 0.83 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL28069148 | 0.82 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL15800382 | 0.82 | NR1H2 (0.40) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL13621387 | 0.78 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL18125 | 0.78 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL2248044 | 0.78 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL13621398 | 0.78 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109629017-B | Super-bright polyester drawn yarn and preparation method thereof | 江苏恒力化纤股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-5760155-A | PREPARED FROM POLYISOCYANATE, POLYOL, SILANOL-FUNCTIONAL SILICONE INTERMEDIATE; MOISTURE CURABLE AT ROOM TEMPERATURE | AMERON INTERNATIONAL CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0021859-B1 | POLYSILOXANE COMPOSITIONS CURABLE INTO ELASTOMERS AT AMBIENT TEMPERATURE IN THE PRESENCE OF WATER | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-01-19 | — | — | EP | disclosed |