Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 12/20 | 0.43 |
| ▸ | MAOB | P27338 | 10/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 11/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573335 | 0.91 | HTR1F (0.44) | BRD4JAK2JAK1PRMT5EGFR | |
| SCHEMBL8582744 | 0.91 | KCNK3 (0.44) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL8580172 | 0.90 | HTR1F (0.43) | HTR1FSTK17BSTK17AMAPTNPC1 | |
| SCHEMBL8567836 | 0.90 | PRMT5 (0.48) | MAOBPRMT5EGFRHTR1FKMT2A | |
| SCHEMBL8571431 | 0.89 | BRD4 (0.47) | BRD4KMT2AMEN1MAPTNPC1 | |
| SCHEMBL8573321 | 0.88 | MEN1 (0.47) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL8603866 | 0.86 | KMT2A (0.45) | JAK2JAK1STK17BSTK17AKMT2A | |
| SCHEMBL8573391 | 0.85 | MAPT (0.41) | BRD4MAOAMAOBKMT2AMEN1 | |
| SCHEMBL8483964 | 0.85 | SMN1; SMN2 (0.55) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL8568716 | 0.84 | ITK (0.39) | BRD4JAK1HTR1FALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006402-A1 | TREATMENT OF THE COMMON COLD OR ALLERGIC RHINITIS | ELI LILLY AND COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |