Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.50 |
| ▸ | NQO2 | P16083 | 14/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573589 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2HTTTRPV1 | |
| SCHEMBL8574127 | 0.93 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2HTTTRPV1 | |
| SCHEMBL8574129 | 0.93 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2HTTTRPV1 | |
| SCHEMBL8569619 | 0.92 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8569617 | 0.92 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8990805 | 0.92 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2HTTTRPV1 | |
| SCHEMBL8573856 | 0.92 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2HTTTRPV1 | |
| SCHEMBL8574790 | 0.90 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8574792 | 0.90 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8573789 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2HTTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |