Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156670 | 0.92 | NPC1 (0.47) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL13064140 | 0.92 | NPC1 (0.47) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL13283174 | 0.84 | MAPT (0.47) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL12606484 | 0.83 | HTT (0.40) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL13064136 | 0.82 | NPC1 (0.48) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL10181733 | 0.82 | NPC1 (0.46) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL10025002 | 0.82 | NPC1 (0.45) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL13918659 | 0.82 | NPC1 (0.38) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL14421289 | 0.81 | PKM (0.63) | NPC1RAB9AMAPTHSD11B1ELANE | |
| SCHEMBL18386646 | 0.81 | CNR1 (0.41) | NPC1RAB9AMAPTHSD11B1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8141716-B2 | Polysulfone and poly(N-vinyl lactam) polymer alloy and fiber and filter materials made of the alloy | DONALDSON COMPANY, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110135901-A1 | Polysulfone and poly(N-vinyl lactam) polymer alloy and fiber and filter materials made of the alloy | DONALDSON COMPANY, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110117287-A1 | Process for producing modified substrate | UENO YOSHIYUKI | 2011-05-19 | — | — | US | disclosed |
| US-20070187320-A1 | Polysulfone-base permselective hollow fiber membrane bundle and process for producing the same | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2007-08-16 | — | — | US | disclosed |