Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419191 | 0.90 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7396395 | 0.86 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8568210 | 0.84 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14402617 | 0.81 | PDE4B (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8646199 | 0.81 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8557981 | 0.80 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6821602 | 0.80 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6129899 | 0.78 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9067040 | 0.78 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8628197 | 0.78 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777160-A | 1, 4, 4-(trisubstituted) cyclohex-1-ene dimers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |