Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | TOP1 | P11387 | 5/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574291 | 1.00 | SCN5A (0.41) | SCN5AKCNH2TOP1LPLLIPG | |
| Hydrochloric Acid SCHEMBL7497986 | 0.99 | SCN5A (0.40) | SCN5AKCNH2TOP1LPLLIPG | |
| Hydrochloric Acid SCHEMBL7497989 | 0.99 | SCN5A (0.40) | SCN5AKCNH2TOP1LPLLIPG | |
| Hydrochloric Acid SCHEMBL9076010 | 0.94 | SCN5A (0.38) | SCN5AKCNH2SCN9A | |
| SCHEMBL8574325 | 0.92 | KCNH2 (0.40) | SCN5AKCNH2TOP1 | |
| SCHEMBL8577656 | 0.92 | KCNH2 (0.40) | SCN5AKCNH2TOP1 | |
| Hydrochloric Acid SCHEMBL7495496 | 0.91 | KCNH2 (0.40) | SCN5AKCNH2TOP1 | |
| Hydrochloric Acid SCHEMBL7503660 | 0.91 | KCNH2 (0.40) | SCN5AKCNH2TOP1 | |
| SCHEMBL8574368 | 0.91 | SCN5A (0.40) | SCN5AKCNH2TOP1 | |
| Hydrochloric Acid SCHEMBL8572865 | 0.91 | SCN5A (0.39) | SCN5AKCNH2TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |