Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579211 | 0.83 | MAPT (0.51) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL8508257 | 0.80 | DRD2 (0.49) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL10872624 | 0.76 | MAPT (0.59) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL10872963 | 0.76 | DRD2 (0.62) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL10873398 | 0.76 | MAPT (0.68) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL10874221 | 0.74 | MAPT (0.57) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL10873930 | 0.73 | MAPT (0.56) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL11481943 | 0.72 | MAPT (0.85) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL11470218 | 0.72 | MAPT (0.69) | MAPTHPGDTP53HTTNPSR1 | |
| SCHEMBL2541686 | 0.70 | MAPT (0.47) | MAPTHPGDTP53HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998001164-A1 | TRICYCLIC RADIOLABELED D4 RECEPTOR LIGANDS | RESOLUTION PHARMACEUTICALS INC. (CA) | 1998-01-15 | — | — | WO | disclosed |