Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576478 | 0.86 | KDM4E (0.52) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL1546543 | 0.85 | TDP1 (0.46) | GAAHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL8575467 | 0.85 | MAPT (0.53) | HTTALDH1A1MAPTNPSR1 | |
| SCHEMBL8580952 | 0.83 | GAA (0.46) | GAAHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL6922302 | 0.83 | MAPT (0.45) | HTTKDM4EHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL7419408 | 0.81 | GAA (0.74) | GAAHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL8573433 | 0.81 | ABL1 (0.51) | GAAKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL8581653 | 0.80 | HTT (0.45) | GAAHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL8582018 | 0.80 | SLC9A1 (0.45) | GAAHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL8573173 | 0.80 | TSHR (0.44) | HTTALDH1A1SMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |