Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | CREB1 | P16220 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306598 | 0.86 | AKT1 (0.40) | PTGS1PTGS2KDM4EPOLBMAPT | |
| SCHEMBL8427197 | 0.85 | PTGS1 (0.36) | PTGS1PTGS2KDM4EPOLBMAPT | |
| SCHEMBL8572731 | 0.84 | QPCT (0.38) | POLBMAPTADORA3CYP1A1CYP1B1 | |
| SCHEMBL8431327 | 0.81 | KDM4E (0.38) | PTGS1PTGS2KDM4EPOLBMAPT | |
| SCHEMBL8309735 | 0.79 | KDM4E (0.39) | KDM4EPOLBMAPTADORA3CYP1A1 | |
| SCHEMBL8574605 | 0.78 | PTGS1 (0.34) | PTGS1PTGS2KDM4EPOLBMAPT | |
| SCHEMBL8308992 | 0.77 | MAOB (0.39) | KDM4EPOLBMAPTADORA3CYP1A1 | |
| SCHEMBL8310185 | 0.77 | MAOB (0.41) | KDM4EPOLBMAPTADORA3CYP1A1 | |
| SCHEMBL8306988 | 0.77 | CYP1B1 (0.42) | POLBMAPTCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL8306599 | 0.75 | FLT3 (0.47) | KDM4EPOLBMAPTADORA3CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |