Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310185 | 0.98 | MAOB (0.41) | MAOBMAOAPPARGPOLHBRD4 | |
| SCHEMBL8306988 | 0.94 | CYP1B1 (0.42) | MAOBMAOAPPARGABCB1POLB | |
| SCHEMBL8429193 | 0.92 | POLB (0.48) | PPARGKDM4EPOLBMAPTMEN1 | |
| SCHEMBL8306598 | 0.91 | AKT1 (0.40) | POLHABCB1KDM4EPOLBMAPT | |
| SCHEMBL8307532 | 0.91 | L3MBTL1 (0.39) | MAOBMAOAL3MBTL1PPARGPOLH | |
| SCHEMBL8304673 | 0.88 | BRD4 (0.40) | MAOBMAOAPOLHBRD4ABCB1 | |
| SCHEMBL8306914 | 0.85 | CYP1B1 (0.43) | MAOBMAOAPPARGABCB1POLB | |
| SCHEMBL8307688 | 0.82 | MAPT (0.35) | MAOBMAOAPPARGPOLHBRD4 | |
| SCHEMBL8309259 | 0.82 | CYP1B1 (0.56) | L3MBTL1POLHABCB1POLBMAPT | |
| SCHEMBL8427185 | 0.81 | POLB (0.47) | MAOBMAOAPPARGPOLHBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |