Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673587 | 0.87 | POLB (0.41) | POLBCYSLTR2CYSLTR1MAPTKMT2A | |
| SCHEMBL8574722 | 0.86 | POLB (0.37) | POLBCYSLTR2CYSLTR1MAPTKMT2A | |
| SCHEMBL8577606 | 0.83 | POLB (0.42) | POLBMAPTKMT2A | |
| SCHEMBL8571807 | 0.81 | MTTP (0.53) | MTTP | |
| SCHEMBL8576794 | 0.80 | MTTP (0.43) | POLBMTTP | |
| SCHEMBL17729935 | 0.80 | POLB (0.38) | POLB | |
| SCHEMBL8573811 | 0.80 | MTTP (0.54) | MTTP | |
| SCHEMBL8483124 | 0.80 | POLB (0.45) | POLB | |
| SCHEMBL8576822 | 0.79 | MTTP (0.48) | MTTP | |
| SCHEMBL8575135 | 0.78 | BID (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760246-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 1998-06-02 | — | — | US | disclosed |