Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673587 | 0.78 | POLB (0.41) | KDM4EMAPT | |
| SCHEMBL8574722 | 0.78 | POLB (0.37) | MAPTALOX15 | |
| SCHEMBL8575130 | 0.78 | POLB (0.34) | MAPT | |
| SCHEMBL8577606 | 0.74 | POLB (0.42) | KDM4EMAPT | |
| SCHEMBL17729935 | 0.72 | POLB (0.38) | — | |
| SCHEMBL8571807 | 0.72 | MTTP (0.53) | — | |
| SCHEMBL8576822 | 0.69 | MTTP (0.48) | — | |
| SCHEMBL8574720 | 0.69 | KMT2A (0.38) | MAPTALOX15 | |
| SCHEMBL8576694 | 0.67 | PPARA (0.41) | MAPTHSD17B10 | |
| SCHEMBL8573340 | 0.65 | MTTP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760246-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 1998-06-02 | — | — | US | disclosed |